Ex-terminators is a dark comedy centering on Alex (Heather Graham), a lonely accountant whose one act of rage results in her being sentenced to court ordered therapy. There she meets Stella (Jennifer Coolidge), the owner of a small extermination business who uses her car as a weapon; and Nikki (Amber Heard), a dental technician with the face of an angel and the mind of a sociopath. Together these women will form their own "silent revolution", wrecking havoc on the abusive men in their lives.

Quotes director John Inwood, "It's such a privilege to be directing Suzanne Weinert's excellent script, with such an immensely talented cast! Heather, Jennifer, Amber and Matt are such a force and such a pleasure to work with. Every scene exceeds my highest expectations. I tried to follow the essential principle of directing - that more than half the job is casting well. I think we have done just that."